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3 |
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Fig 2—Affected glo-
merulus stained with
anti-mink C3. C3 is
deposited along the
basement mem-
branes and mesa ngial
areas. A similar pat-
tern was seen with
anti-mink IgG.
the virus remains present in the high titer.’4 These findings further incriminate
the immune
response
of the host in the development of lesions in this disease.
Comparison with Human Disease
Some human diseases are caused by or have been suggested to be the
result of persistent viral infections. These include such conditions as infec-
tious hepatitis, subacute scierosing panencephalitis, kuru, Creutzfeld-Jakob
Fig 3—Fibrinoid necrosis of small muscular artery in the kidney. There is perivas-
cular infiltration of mononuclear cells (principally plasma cells) and neutrophils
within the necrotic media.
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